CANCELED: 13th University of Pennsylvania Conference on Statistical Issues in Clinical Trials:

CANCELED: 13th University of Pennsylvania Conference on Statistical Issues in Clinical Trials:



TOPIC:  Cluster Randomized Clinical Trials:

Challenges and Opportunities

April 29, 2020

(Updated 3/20/2020)   We regret to announce that due to concerns about the spread of Coronovirus and related restrictions the University has put in place, we are cancelling our 13th Annual Conference on Statistical Issues in Clinical Trials that had been scheduled for April 29, 2020. We are working on rescheduling this popular event in April 2021.

We can confirm that refunds have been processed as of 3/19/20.  It may take 5-7 business days for this to be reflected and if individuals paid by check, it may take up to 90 days to get back to them due to the current situation, but hopefully sooner.

Please check back here for updates.

Registration opens January 1, 2020



Arthur H. Rubenstein Auditorium

UPenn Campus - Philadelphia, PA 19104

7:30 AM - 8:30 AM / Breakfast and Registration

8:30 AM - 4:30 PM / Conference




David Murray, PhD (NIH)

Overview:  Innovations in Design and Analysis of Group or Cluster Randomized Trials

Victor DeGruttola, ScD  (Harvard)

Using network-and individual-level information in design and analysis of clustered trials

Luke J. Keele, PhD (University of Pennsylvania)

Complexities Caused by Noncompliance in Cluster Randomized Trials

James P. Hughes, PhD (University of Washington)

Current issues in the design and analysis of stepped wedge trials


Lawrence H. Moulton, PhD (Johns Hopkins University)

Randomization:  Beyond the Closurization Principle

Ira Longini, PhD (University of Florida)

The ring vaccine trial design for the estimation of vaccine efficacy and effectiveness during infectious disease outbreaks

Deborah J. Donnell, PhD (University of Washington)

Challenges for implementing CRTs: from Hawthorne effect to measurement bias

Weili He, PhD (AbbVie)

Practical considerations in utilizing cluster randomized trials in medical research


Karla Hemming, PhD University of Birmingham
David Murray, PhD National Institutes of Health
Michael Proschan, PhD National Institutes of Health
Jeffrey Roberts, MD US Food and Drug Administration
Alisa Stephens-Shields, PhD University of Pennsylvania
Monica Taljaard, PhD Ottowa Hospital Research Institute

A current version of this year's detailed program can be found here (PDF).

Check out last year's program here (PDF).


Registration and Fees

Industry: $275

Academic and Government: $175

Upenn Faculty and Students: $0

Non-Penn Students: $75


American Statistical Association - 2020 Annual Meeting Information

Society for Clinical Trials - 2020 Annual Meeting Information

National Institute of Statistical Sciences - 8th Workshop on Biostatistics and Bioinformatics


The Conference will be held in the Arthur H. Rubenstein Auditorium at the Smilow Center for Translational Research on the campus of the University of Pennsylvania Perelman School of Medicine. A campus map can be found HERE.

Event Day Parking

Day parking for the event is available for purchase in advance for a $20 fee. Event day parking is located at the Curie Garage, 426 Curie Boulevard on Penn's campus. To secure a space, participants were asked to request parking during online registration. A map of Curie Garage and conference location can be found HERE.  Conference attendees staying overnight were asked to contact their hotel for overnight parking information.


The Study at University City is located within easy alking distance to the conference.  A limited number of rooms are secured at The Study at University City at the discounted rate of $229.  Reservations are also available by phone (215-387-1400) referencing "Statistical Issues in Clinical Trials" for the discount.  Many alternative hotels in Center City Philadelphia are also a short distance from the UPenn campus.  Participants were encouraged to make their housing arrangements as soon as possible.


Arthur H. Rubenstein Auditorium
Smilow Center for Translational Research (SCTR)
Perelman School of Medicine
University of Pennsylvania
3400 Civic Center Boulevard
Philadelphia, PA 19104

For additional information, contact:
Janine Pritchard
Phone: 215-573-4045 | Email:


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