12th Annual Conference on Statistical Issues in Clinical Trials

Wednesday, April 17, 2019
7:30 am - 5:00 pm
04/17/19 - 7:30am to 04/17/19 - 5:00pm
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Electronic Health Records (EHR) in Randomized Clinical Trials: Challenges and Opportunities

Speakers/Panelists and Topics

Denise Esserman, PhD
Yale University
From Screening to Ascertainment of the Primary Outcome using EHR, Challenges in the STRIDE Trial
Steven Zeliadt, PhD
University of Washington
The APPROACH Trial: Assessing Pain, Patient Reported Outcomes and Complementary and Integrative Health
Richard Platt, MD, MSc
Harvard Medical School and
Harvard Pilgrim Health Care Institute
The IMPACT-AFib Trial: IMplementation of an RCT to imProve Treatment with Oral AntiCoagulanTs in Patients with Atrial Fibrillation
Matthew T. Roe, MD
Duke University
Leveraging Electronic Health Record Data for Pragmatic
Randomized Trials in Learning Health Care Systems in the United States – Lessons Learned from the ADAPTABLE Trial
Benjamin A. Goldstein, PhD
Duke University.
Design Considerations for Running Health System Based Trials Through the Electronic Health Record
Mark Levenson, PhD
Food and Drug Administration
Regulatory perspective to performing RCTs in an EHR environment
Patrick J. Heagerty, PhD
University of Washington
Addressing heterogeneity in the data, design, and analysis of pragmatic trials embedded in delivery systems
Susan M. Shortreed, PhD
Kaiser Permanente
Washington Health Research Institute
Using real-world data to improve trial design
Jinbo Chen, PhD
University of Pennsylvania
Study design issues for exploiting EHRs to design clinical trials
Rebecca Hubbard, PhD
University of Pennsylvania
Clinical Trials in the Age of Data Science
Bill Capra, PhD

To view or download presentation slide sets, please click on the topic in the table above.
Short biographies for each speaker/panelist are available for download here.


Other Co-Sponsors

University of Pennsylvania Center for Clinical Epidemiology and Biostatistics
and Department of Biostatistics, Epidemiology and Informatics

American Statistical Association - 2019 Annual Meeting Information

National Institute of Statistical Sciences – Newsletter

Society for Clinical Trials - 2019 Annual Meeting Information


For additional information, contact:

Janine Pritchard, jpritcha@pennmedicine.upenn.edu or 215-573-4045


Wednesday, April 29, 2020 (8:00 A.M. to 5:00 PM)

13th Annual University of Pennsylvania
Conference on Statistical Issues in Clinical Trials:

Cluster Randomized Clinical Trials: Challenges and Opportunities

Registration opens January 2020