This is an advanced course that addresses epidemiologic research issues as they apply to important clinical topics in obstetrics and gynecology and related clinical disciplines. Lectures and workshops are designed to acquaint students with important issues in the field of reproductive epidemiology, to use a body of literature to demonstrate the strengths and weaknesses of epidemiologic research designs as they have been applied to obstetrics and gynecology and related clinical disciplines, to expose students to the range of topics studied, to teach advanced epidemiologic principles using a problem-based approach, and to stimulate students interested in reproductive epidemiology to develop independent research questions.