Dr. Leonard is a pharmacoepidemiologist whose work focuses on generating rigorous, policy-relevant evidence on medication safety and effectiveness using real-world data. His research integrates advanced causal inference methods with large healthcare databases to address clinically meaningful questions, particularly in complex treatment settings and among vulnerable populations.
Within the CCEB, Dr. Leonard collaborates with investigators across disciplines to design and execute studies that inform clinical decision-making and regulatory evaluation. His methodological interests include self-controlled designs, pharmacoepidemiologic approaches to drug interactions, and strategies to strengthen causal inference from observational data. He is also a member of the Center’s Executive Advisory Committee.
Dr. Leonard’s work has contributed to clinical and policy discussions on medication safety, and he is committed to translating epidemiologic evidence into practice. He plays a central role in training the next generation of clinical epidemiologists, with an emphasis on bridging methodological rigor and real-world applicability.
Content Area Specialties
Pharmacoepidemiology, comparative safety, drug interactions, real-world evidence, sudden cardiac arrest, type 2 diabetes mellitus
Methods Specialties
High-dimensional propensity scores, observational studies, propensity scores, proportional hazards regression, self-controlled case series design