Research

CFAR logo

Penn Center for AIDS Research (CFAR)

Funding: NIAID
Investigators: Hoxie, JA; Ellenberg, SS

The Penn Center for AIDS Research (Penn-CFAR) is one of 18 NIH-funded CFARs, and includes HIV and AIDS investigators at the University of Pennsylvania, the Children's Hospital of Philadelphia (CHOP), and the Wistar Institute.

HOPE Helping People on Dialysis Manage Pain logo

The Hemodialysis Opioid Prescription Effort (HOPE) Consortium

Funding: NIDDK
Investigator: Dember, L.

The HOPE Trial is an NIDDK-funded randomized clinical trial to evaluate approaches to reducing pain and opioid use among patients with chronic pain who are receiving maintenance hemodialysis for end-stage renal disease.

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A Trial of Transplanting Hepatitis C Kidneys into Hepatitis C-Negative Kidney Recipients (THINKER-NEXT)

Funding: NIDDK
Investigator: Reese, P; Schaubel, D; Goldberg, D

The CRCU serves as the Data Coordinating Center for the THINKER-NEXT trial. The THINKER-NEXT trial, led by Peter Reese, MD and Douglas Schaubel PhD at The Perelman School of Medicine and David Goldberg, MD at the University of Miami in Florida, is a single arm open-label NIDDK-funded clinical trial.  The main objective of the study is to estimate the hepatitis C virus (HCV) cure rate after transplantation, using kidneys from HCV-infected deceased donors for HCV-negative recipients, followed by treatment with direct acting antivirals

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CRIC Ancillary Studies

The Scientific and Data Coordinating Center at Penn receives data and provides ongoing support for a number of Ancillary Studies supported by the CRIC Cohort utilizing both CRIC study participants and biological samples obtained from CRIC study participants. Through the CRIC data sharing policy, investigators have an opportunity to tap into the rich CRIC data to pursue their own research goals.

In addition to the CRIC Clinical Centers listed on the Participating Institutions page, collaborative research partnerships are currently conducted at a number of institutions across the country including, but not limited to, University of Utah, University of Miami, University of North Carolina, George Washington University, University of Alabama, as well as at international sites in China, Japan, Peru, and Germany 

A selection of CRIC Ancillary Studies managed by the CRCU appears below: