The Scientific and Data Coordinating Center at Penn receives data and provides ongoing support for a number of Ancillary Studies supported by the CRIC Cohort utilizing both CRIC study participants and biological samples obtained from CRIC study participants. Through the CRIC data sharing policy, investigators have an opportunity to tap into the rich CRIC data to pursue their own research goals.
In addition to the CRIC Clinical Centers listed on the Participating Institutions page, collaborative research partnerships are currently conducted at a number of institutions across the country including, but not limited to, University of Utah, University of Miami, University of North Carolina, George Washington University, University of Alabama, as well as at international sites in China, Japan, Peru, and Germany
A selection of CRIC Ancillary Studies managed by the CRCU appears below:
Brigham and Women's Hospital PI: WAIKAR
Start: 9/1/2015
End: 8/31/2020
Project Title: Oxalate in CKD Pathogenesis and Progression
CHOP PI: LEONARD
Start: 10/1/2014
End: 8/31/2015
Project Title: Performance of Vitamin D-Binding Protein (DBP) ELISA by Genotype: Validation Using Mass Spectometry
CLEVELAND CLINIC PI: NAVANEETHAN
Start: 9/22/2014
End: 7/31/2020
Project Title: Visceral Adiposity and Fitness among CRIC Participants
CLEVELAND CLINIC PI: TANG
Start: 9/14/2015
End: 7/31/2020
Project Title: Trimethylamine N-Oxide and Disease Progression in CKD
Harvard PI: STROM
Start: 7/1/2023
End: 6/30/2028
Project Title: Chronic Renal Insufficiency and Silent Progression of Aortic Stenosis (CRISP-AS)
Harvard PI: WOLF
Start: 8/1/2008
End: 7/31/2012
Project Title: Genetics of Race and Disordered Mineral Metabolism in CKD
Johns Hopkins PI: ISHIGAMI
Start: 8/4/2021
End: 5/31/2026
Project Title: Patient Perceptions about Influenza Vaccination in Nephrology Care
Mass. Gen. Hospital PI: KALIM
Start: 4/1/2018
End: 3/31/2020
Project Title: The Effects of Protein Carbamylation in Chronic Kidney Disease
Mass. Gen. Hospital PI: RHEE
Start: 9/14/2015
End: 7/31/2020
Project Title: Metabolomics and CKD Progression in CRIC
Northwestern PI: ISAKOVA
Start: 9/20/2016
End: 6/30/2021
Project Title: Impact of serum calcification propensity on adverse outcomes in CKD
PENN/SOM PI: ANDERSON
Start: 9/20/2016
End: 6/30/2021
Project Title: The Gut Microbiome and the Metabolome in CKD
PENN/SOM PI: ANDERSON
Start: 4/1/2015
End: 3/31/2020
Project Title: Measures of Fibrosis and Clinical Outcomes in Chronic Kidney Disease
PENN/SOM PI: DEO, Rajat
Start: 1/1/2018
End: 12/31/2019
Project Title: Soluble Fms-Like Tyrosine Kinase-1 (sFlt-1), Placental Growth Factor (PlGF) and Cardiovascular Disease in Participants with Chronic Kidney Disease
PENN/SOM PI: FELDMAN
Start: 9/1/2009
End: 6/30/2023
Project Title: CKD Biomarkers Consortium
PENN/SOM PI: FELDMAN
Start: 7/1/2001
End: 6/30/2023
Project Title: Chronic Renal Insufficiency Cohort
PENN/SOM PI: FELDMAN
Start: 5/1/2016
End: 4/30/2021
Project Title: CRIC Queryable Database
PENN/SOM PI: FELDMAN
Start: 5/1/2016
End: 4/30/2018
Project Title: CRIC Phase IV Pilots
PENN/SOM PI: FELDMAN
Start: 9/1/2006
End: 8/31/2011
Project Title: CKD, Metabolic Syndrome and Cardiovascular Disease
PENN/SOM PI: GRUNWALD
Start: 3/1/2006
End: 2/28/2011
Project Title: Retinopathy in Chronic Renal Insufficiency (CRI)
PENN/SOM PI: KY
Start: 7/1/2009
End: 6/30/2014
Project Title: The Role of Neuregulin in Human Cardiac Remodeling and Heart Failure
PENN/SOM PI: RADER
Start: 8/1/2009
End: 5/31/2014
Project Title: Genetic of Lipoprotein Metabolism and CVD in CKD
PENN/SOM PI: ROSAS
Start: 7/1/2008
End: 6/30/2013
Project Title: Carotid Intima-Media Thickness in Chronic Kidney Disease
PENN/SOM PI: SUSZTAK
Start: 7/1/2015
End: 6/30/2021
Project Title: The Clinical Relevance of Epigenetic Dysregulation in Diabetic Kidney Disease
PENN/SOM PI: TOWNSEND
Start: 8/1/2010
End: 7/31/2014
Project Title: Pulse Wave Velocity
PENN/SOM PI: TOWNSEND
Start: 11/20/2012
End: 11/20/2013
Project Title: CRIC Penn Site CTMS Replacement
PENN/SOM PI: WILSON
Start: 7/15/2013
End: 4/30/2018
Project Title: Mediators & Prognostic Value of Muscle Mass & Function in Chronic Kidney Disease
Stanford PI: SIRICH
Start: 7/1/2014
End: 6/30/2019
Project Title: Novel Metabolites Associated with Renal Outcomes
TuftsU PI: INKER
Start: 12/15/2020
End: 11/30/2024
Project Title: Improving Kidney Function Assessment in Health and Disease
TuftsU PI: SHEA
Start: 2/1/2017
End: 1/31/2020
Project Title: Vitamin K Status, CVD and Arterial Stiffness in Chronic Kidney Disease
Tulane PI: CHEN, Jing
Start: 8/15/2021
End: 7/31/2024
Project Title: Establishing A New Diagnostic Paradigm in Assessing Peripheral Artery Disease among Patients with Chronic Kidney Disease
Tulane PI: KELLY
Start: 5/13/2021
End: 3/31/2026
Project Title: Consequences of Clonal Hematopoiesis ofIndeterminate Potential (CHIP) in Chronic KidneyDisease
Tulane PI: KELLY
Start: 9/1/2015
End: 5/31/2020
Project Title: Whole-Exome Sequencing Study of Diabetic Nephropathy
Tulane PI: LI (Changwei)
Start: 7/1/2022
End: 6/30/2025
Project Title: Metabolomics Study of APOL1-Associated Progression of Chronic Kidney Disease
UAlabama PI: KRICK
Start: 8/15/2022
End: 10/15/2022
Project Title: Pilot study: Association between kidney function, FGF23 and lung impairment
UAMS PI: SHAH
Start: 8/15/2010
End: 6/30/2012
Project Title: Carbamylated LDL and Cardiovascular Events
UCSD PI: SHARMA
Start: 9/30/2011
End: 6/30/2016
Project Title: Novel Paradigm to Understand Diabetic Complications
UCSF PI: BANSAL
Start: 8/25/2015
End: 7/31/2020
Project Title: Heart failure and Arrhythmias in CKD
UCSF PI: BANSAL
Start: 9/15/2010
End: 6/30/2015
Project Title: Hypertension in Advanced Chronic Kidney Disease
UCSF PI: DUBIN
Start: 5/14/2021
End: 4/30/2025
Project Title: Elucidating the Biology of Cardiovascular Risk inHemodialysis Patients Using Proteomics
UCSF PI: GANZ
Start: 8/19/2016
End: 7/31/2021
Project Title: Identifying Modifiable Biomarkers/Mediators for Cardiovascular Disease in CKD
UCSF PI: HSU/LIU
Start: 9/1/2009
End: 6/30/2023
Project Title: Acute Kidney Injury in Chronic Kidney Disease
UCSF PI: SHLIPAK
Start: 5/15/2023
End: 3/31/2028
Project Title: Development of a Kidney Biomarker Panel to Detect and Quantify NSAID Damage among Persons with CKD
UCSF PI: YAFFE
Start: 9/1/2011
End: 5/31/2015
Project Title: Cognitive Function in CRI - Evaluating the Trajectory of Cognitive Function in Persons with CKD
UIC PI: LASH
Start: 4/1/2011
End: 8/31/2023
Project Title: Hispanic Chronic Renal Insufficiency Cohort
UIC PI: LASH
Start: 8/20/2012
End: 7/31/2017
Project Title: Health Disparities in Children and Adults with Kidney Disease Mentoring Program
UIC PI: PUZANTIAN
Start: 10/1/2015
End: 9/30/2020
Project Title: Arterial Stiffness and Proteinuria in CKD: Role of Vascular Biomarkers in Disease Progression
UIC PI: RICARDO
Start: 6/1/2019
End: 5/31/2024
Project Title: Sleep Disordered Breathing as a Predictor of Outcomes in Chronic Kidney Disease
UIC PI: RICARDO
Start: 5/1/2013
End: 2/28/2018
Project Title: Gender Disparities and Endogenous Estrogen in Chronic Kidney Disease
UIllinois PI: LORA
Start: 6/15/2014
End: 3/31/2016
Project Title: Validation of the Kidney Knowledge Survey (KIKS) in Hispanics with CKD
UMaryland PI: DIAMANTIDIS, Clarissa
Start: 6/1/2014
End: 5/31/2018
Project Title: Can Health IT Tools be used in CKD?
UMaryland PI: FINK
Start: 9/1/2011
End: 8/31/2016
Project Title: Do Patient Safety Events Account For Adverse Outcomes In CKD?
UMiami PI: ISAKOVA
Start: 10/31/2013
End: 10/31/2015
Project Title: Role of Sclerostin in Disordered Mineral Metabolism in CKD (Gottschalk)
UMiami PI: SCIALLA
Start: 7/1/2012
End: 4/30/2017
Project Title: CRIC AP - Net Acid Excretion and Morbidity in CKD
UMiami PI: WOLF
Start: 8/1/2012
End: 7/31/2018
Project Title: Genetics of Race and Disordered Mineral Metabolism in CKD
UMiami PI: WOLF
Start: 7/31/2014
End: 7/30/2015
Project Title: FGF23 and Clinical Outcomes in ADPKD Patients
UMichigan PI: AFSHINNIA
Start: 9/17/2015
End: 7/31/2020
Project Title: Identification-Validation of Prognostic Biomarkers in Chronic Kidney Disease
UMichigan PI: AFSHINNIA
Start: 8/1/2013
End: 7/31/2014
Project Title: Identification-Validation of Prognostic Biomarkers in Chronic Kidney Disease - (Pilot study)
UMichigan PI: KRETZLER
Start: 7/1/2008
End: 6/30/2013
Project Title: Molecular Predictors of Progressive Renal Failure in the Chronic Renal Insufficiency Cohort
UMinesota PI: DRAWZ
Start: 7/1/2010
End: 6/30/2015
Project Title: Elevated nighttime BP - clinical and demographic features, correlates, and changes over time
UNM PI: ARGYROPOULOS
Start: 7/1/2017
End: 6/30/2022
Project Title: MicorRNAs in Progressive Renal Disease - a Pilot Study in CRIC
UNM PI: RAJ
Start: 9/1/2006
End: 6/30/2011
Project Title: Cytokine Gene Polymorphism in CRIC
UNM PI: SHAH
Start: 7/9/2019
End: 6/30/2024
Project Title: American Indian Chronic Renal Insufficiency Cohort Study (AI CRIC Study)
UTexas PI: NOVICK
Start: 7/1/2021
End: 6/30/2023
Project Title: The Accountable Health CommunitiesHealth-Related Social Needs Screening Tool - CRIC opportunity pool
UUtah PI: CHEUNG, Alfred
Start: 8/27/2013
End: 6/30/2018
Project Title: Pathophysiological Role of Prorenin
UUtah PI: CHO, Monique
Start: 4/1/2018
End: 3/31/2023
Project Title: The role of iron deficiency in cardiac and diabetic complications of CKD
UWashington PI: DE BOER, Ian
Start: 4/15/2014
End: 2/28/2018
Project Title: 24,25-Dihydroxyvitamin D in CRIC
UWashington PI: KESTENBAUM
Start: 4/1/2016
End: 3/31/2020
Project Title: Kidney Secretions and Chronic Kidney Disease Complications
WashingtonU PI: HERRLICH
Start: 9/15/2019
End: 8/31/2024
Project Title: sAREG in Urine and Serum as a Biomarker of CKD severity and Progression