Xinhua Chen, MD, MSCE
|CCEB Appointment||Adjunct Scholar, Epidemiology|
|Non-Penn Appointment||Research Teaching Specialist, Department of Obstetrics and Gynecology|
University of Medicine and Dentistry of New Jersey
My research interest is to study carbohydrate and lipid metabolism in type 2 diabetes and gestational diabetes. Our research group has conducted studies on the associations among the factors such as metabolic abnormalities, chronic inflammation, oxidative stress and antioxidants with risk of adverse maternal-fetal outcomes. Recently we have completed the project of oxidative stress and poor pregnancy outcomes. The nest step is to explore the possible mechanisms on these new findings.
Chen X, Scholl TO, Stein TP. Association of elevated serum ferritin levels and the risk of gestational diabetes mellitus in pregnant women – Camden Study. Diabetes Care 2006; 29: 1077-82.
Chen X, Scholl TO, Leskiw MJ, Donaldson MR, Stein TP. Association of glutathione peroxidase activity with insulin resistance and dietary fat intake during normal pregnancy. J Clin Endocrinol Metab 2003; 88: 5963-8.
Chen X, Scholl TO. Ethnic differences in C-peptide/insulin/glucose dynamics in young pregnant women. J Clin Endo Metabol 2002; 87: 4642-6.
Scholl TO, Chen X, Gaughan C, Smith W. Maternal glucose: influence on the ethnic difference in birth weight and pregnancy outcome. Am J Epidemiol 2002; 156: 498-506.
Chen X, Iqbal N, Boden G. Effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects. J Clin Invest 1999; 103: 365-72.