Ron Keren, MD, MPH
|CCEB Appointment||Senior Scholar, Epidemiology|
|Primary Faculty Appointment||Associate Professor of Pediatrics at CHOP, University of Pennsylvania Perelman SOM|
|DBE Appointment||Associate Professor of Epidemiology|
My research focus is the effectiveness and cost-effectiveness of treatments for common problems in general pediatrics. My current research includes the prediction and prevention of newborn hyperbilirubinemia and kernicterus, the therapeutic and radiological management of children with urinary tract infections (UTIs) and the epidemiology and economics of influenza.
The study designs and research methods I use are dictated by my research questions. To date, they include prediction model development, diagnostic test evaluation, cost-effectiveness analysis, meta-analysis, survey methods, case-control studies and observational study designs. I am currently the site principal investigator for a multi-center randomized placebo-controlled trial of prophylactic antibiotics for children with vesicoureteral reflux (the retrograde flow of urine during bladder contraction).
I am also interested in medical education and am the co-founder and instructor of a monthly seminar to teach pediatric residents skills for practicing evidence based pediatrics. With support from a Foerderer Foundation grant, I developed a Web-based library of images from clinical pediatrics. The Walter W. Tunnessen Pediatric Image Library contains over 4,000 cases and 10,000 images contributed by multiple clinicians at Children's Hospital. The library serves as an educational resource and reference for students and pediatric providers.
Conway, P. H., Cnaan, A., Zaoutis, T., Henry, B. V., Grundmeier, Keren, R., Luan, X., Friedman, S., Saddlemire, S., Cnaan, A., Bhutani, V. K. A Comparison of Alternative Risk Assessment Strategies for Predicting Severe Neonatal Hyperbilrubinemia. Pediatrics 2008;121(1):e170-9.
R. W., Keren, R. Recurrent Urinary Tract Infections: Risk Factors and Effectiveness of Prophylaxis in a Primary Care Cohort, JAMA 2007;298(2):179-86. (Featured in JAMA Video News Release)
Keren, R., Zaoutis, T., Saddlemire, S., Luan, X., Coffin, S. Direct Medical Costs of Influenza-related Hospitalizations in Children. Pediatrics 2006;118(5):e1321-7.
Keren R, Zaoutis TE, Bridges CB, Herrera G, Watson BM, Wheeler AB, Licht DJ, Luan XQ, Coffin SE. Neurological and neuromuscular disease as a risk factor for respiratory failure in children hospitalized with influenza infection. JAMA 2005;294(17):2188-94. (Featured in JAMA Video News Release)
Keren R, Bhutani VK, Luan X, Nihtianova S, Cnaan A, Schwartz JS. Identifying newborns at risk of significant hyperbilirubinaemia: a comparison of two recommended approaches. Arch Dis Child. 2005;90(4):415-21.