Biostatistics: 2014 Annual Conference on Statistical Issues in Clinical Trials

University of Pennsylvania
Center for Clinical Epidemiology and Biostatistics
Department of Biostatistics and Epidemiology
7th Annual Conference on
Statistical Issues in Clinical Trials

April 8, 2014

Topic for 2014 Conference:
Current Issues Regarding the Use of Biomarkers and Surrogate Endpoints in Clinical Trials

Arthur H. Rubenstein Auditorium
Smilow Center for Translational Research (SCTR)
Perelman School of Medicine
University of Pennsylvania
3400 Civic Center Boulevard
Philadelphia, PA 19104

The 2014 Conference will bring together leading scientists who will discuss state-of-the-art approaches for using biomarkers and surrogate endpoints in the design, analysis and interpretation of clinical trials. Participants from academic institutions, industry, and government agencies with an interest in clinical trials methodology are encouraged to register.


American Statistical Association - 2014 Annual Meeting Information
Society for Clinical Trials - 2014 Annual Meeting Information
University of Pennsylvania Center for Clinical Epidemiology and Biostatistics
Faculty Institution Topic
Stuart Baker National Cancer Institute

Evaluating surrogate endpoints, risk prediction markers, and treatment benefit markers: some simple themes

Marshall Joffe University of Pennsylvania Surrogate outcomes for time-varying treatments and outcomes, including SMART trials
Jeremy Taylor University of Michigan Surrogacy assessment using principal stratification
Jarcy Zee University of Pennsylvania Survival analysis with both surrogate and true endpoints by using an internal validation subsample
Michael Kattan Cleveland Clinic Evaluating biomarkers using Incremental predictive accuracy
Ying Huang Fred Hutchinson Cancer Research Center Identifying optimal biomarker combinations for treatment selection through randomized controlled trials
Herbert Weisberg Causalytics, LLC Post hoc subgroups: Anathema or analytics?


H.M. James Hung Food and Drug Administration Discussion/Comments
Constantine Frangakis Johns Hopkins University Discussion/Comments
Michael Daniels University of Texas at Austin Discussion/Comments
Eve H. Pickering Pfizer, Inc. Discussion/Comments
Lurdes Y. T. Inoue University of Washington Discussion/Comments
Debashis Ghosh Pennsylvania State University Discussion/Comments


A PDF version of the agenda is available for download.


For additional information, contact:
Marissa Fox
Phone: 215-573-2728   Email:

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